Anti-Tuftelin 1 Antibody

This rabbit polyclonal reagent from Antibodies.com targets Tuftelin 1 (TUFT1), an acidic enamel matrix glycoprotein first characterized in developing tooth enamel and now studied broadly in extra-oral tissues. TUFT1 has attracted attention in cancer biology, with published reports linking its expression to breast, ovarian, gastric, and hepatocellular carcinoma, where it has been implicated in epithelial-mesenchymal transition and hypoxia-related signalling.

Supplied as 100 µl of unconjugated antiserum, the antibody is validated for Western blot and immunohistochemistry on human samples, giving laboratories a practical tool for mapping TUFT1 distribution in normal epithelium, dental hard tissues, and tumour biopsy material. The polyclonal format increases the likelihood of recognising multiple epitopes across the TUFT1 sequence, which is useful when probing tissues where post-translational modifications or splice variation may influence antibody binding.

Working dilutions should be optimised empirically for each application, as optimal titres depend on tissue type, fixation method, and detection chemistry. Short term, refrigerate the vial; for longer storage, aliquot and freeze, avoiding repeated freeze-thaw cycles to preserve activity.