Anti-Tubulin beta-8 Antibody

Raised in rabbit, this unconjugated polyclonal antibody selectively targets the Tubulin beta-8 (TUBB8) isotype in human samples.

Supplied as 100 µl of liquid, the reagent supports three orthogonal detection workflows: Western blot on cell lysate, immunohistochemistry on fixed tissue sections, and immunofluorescence on cultured cells. The unconjugated format gives laboratories the freedom to conjugate the antibody to fluorophores, enzymes, or biotin in-house for tailored imaging and signal-amplification protocols.

Tubulin beta-8 occupies a distinctive niche within the beta-tubulin family. Unlike broadly expressed isotypes such as TUBB and TUBB5, TUBB8 is predominantly associated with oocyte meiotic spindle assembly and has become a focal target in reproductive biology research, particularly in studies of female infertility, oocyte maturation arrest, and failed fertilization cycles, where specific sequence variants have been linked to defective meiotic spindle organization.

Antibodies.com supplies the reagent in a 100 µl vial with reactivity restricted to human samples, so laboratories studying oocyte development, embryogenesis, or cytoskeletal architecture in mouse or other model systems will need a parallel species-matched reagent.