Anti-Tubulin alpha-1B Antibody

Raised in rabbit and supplied as an unconjugated polyclonal reagent in a 100 µl vial, this primary antibody from Antibodies.com specifically recognises Tubulin alpha-1B (TUBA1B), a widely expressed alpha-tubulin isotype that forms the heterodimeric core of cellular microtubules. The antibody is validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human samples.

TUBA1B contributes to cytoskeletal architecture, mitotic spindle assembly, and intracellular trafficking, and it has been the focus of recent expression-profiling studies in oncology where its abundance has been associated with tumour grade and with sensitivity to microtubule-targeting drugs. Resolving TUBA1B from the brain-enriched paralogue TUBA1A is therefore important when profiling non-neural tissues or interpreting mass-spectrometry datasets that separate tubulin isoforms.

Because the reagent is unconjugated, it pairs with any labelled secondary antibody, allowing flexible assay design across fluorescence, chromogenic, and chemiluminescent readouts. Store refrigerated; avoid repeated freeze-thaw cycles to preserve titre. For research use only.