Anti-TUBA4A Antibody

TUBA4A encodes the tubulin alpha-4A chain, a cytoskeletal protein that incorporates into microtubules and supports intracellular transport, cell shaping, and mitotic spindle assembly. This unconjugated rabbit polyclonal reagent from Antibodies.com was raised against the TUBA4A target and is validated for Western blot (WB) and immunohistochemistry (IHC) workflows on human, mouse, and rat samples.

The antibody is supplied as 100 µl of liquid stock in a vial, aliquoted for typical single-experiment use, and is intended for research use only. Its broad species reactivity makes it well matched to comparative work in established cell lines, primary cultures, and fixed tissue sections, while the unconjugated format allows researchers to pair it with secondary reagents of their choice for fluorescence, chromogenic, or chemiluminescent readout.

TUBA4A has attracted strong interest in neuroscience because coding mutations have been linked to familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Investigators studying neuronal cytoskeletal integrity, axonal transport defects, and motor neuron degeneration pathways can use this reagent to track endogenous TUBA4A expression, map subcellular localization, and compare control versus disease-model systems at the protein level.