Anti-TTPA Antibody

Produced for Western blot detection of human alpha-tocopherol transfer protein, this rabbit polyclonal IgG reagent from Antibodies.com is supplied as a 50 µl vial of unconjugated affinity-purified stock in PBS buffer. The target (TTPA) is the cytoplasmic carrier that mediates transfer of α-tocopherol between intracellular membranes, concentrating in liver parenchyma and select neural tissues; loss-of-function variants cause ataxia with vitamin E deficiency (AVED), making reliable detection of endogenous TTPA valuable to research on lipid trafficking, antioxidant homeostasis, and inherited cerebellar ataxias. Standard immunoblotting of whole-cell lysates from hepatocellular lines and patient-derived fibroblasts resolves a primary band near the predicted 32 kDa molecular weight. For research use only in in vitro studies; store refrigerated with working stock aliquoted to limit freeze-thaw across the reagent's working shelf life.