Anti-TTK (Ab-676) Antibody

Raised in rabbit and affinity-purified by epitope-specific immunogen chromatography, this polyclonal reagent from Antibodies.com is directed against the dual specificity protein kinase TTK (also known as MPS1, MPS1L1 or PYT) and was generated using a synthesized non-phosphopeptide derived from human TTK surrounding the threonine 676 phosphorylation site (D-T-T(p)-S-V). The antibody is unconjugated and supplied as Rabbit IgG in phosphate-buffered saline (pH 7.4) without Mg²⁺ and Ca²⁺, containing 150 mM NaCl, 0.02% sodium azide and 50% glycerol, at a working concentration of 1.0 mg/mL. It is offered in a 50 µL volume and is validated for Western blotting (WB) and immunohistochemistry (IHC) on human samples, where it detects endogenous levels of total TTK protein. The reagent is shipped at 4 °C and should be aliquoted upon arrival and stored at –20 °C, with freeze/thaw cycles avoided to preserve activity. Suitable dilutions reported on similar lots range from 1:500–1:3000 for WB and 1:50–1:100 for IHC, making this Antibodies.com primary antibody a convenient choice for researchers characterising TTK expression and signalling in cell and tissue-based assays.