Anti-TTC8 Antibody

This rabbit polyclonal IgG antibody recognizes TTC8, the tetratricopeptide repeat protein also known as BBS8. TTC8 is a core component of the BBSome complex that localizes to centrosomes and the basal body, where it supports membrane recruitment and intraflagellar trafficking in primary cilia. The reagent is raised in rabbit, supplied as an unconjugated polyclonal antibody in a 100 µl vial, and validated for western blot detection of the human protein.

Investigators working on Bardet-Biedl syndrome and related ciliopathies use TTC8 antibodies to probe BBSome assembly and ciliary transport in patient-derived cell lines and tissue lysates. For best results, aliquot upon receipt and store at -20 °C, avoiding repeated freeze-thaw cycles. Antibodies.com provides this primary antibody for research use only, supporting studies that link BBS8 variants to retinal degeneration, renal anomalies, and the obesity-polydactyly spectrum typical of BBS type 8.