Anti-TSPAN7 Antibody

This polyclonal antibody from Antibodies.com targets TSPAN7 (Tetraspanin 7), a four-pass transmembrane protein of the tetraspanin superfamily, also referenced as TM4SF7 or TALLA-1. Raised in rabbit and supplied unconjugated in a 100 µl volume, the reagent is validated for Western blot and immunofluorescence workflows and recognizes both human and mouse TSPAN7, enabling cross-species studies in neuronal and tumor biology contexts.

TSPAN7 contributes to membrane microdomain organization, cell-cell adhesion, and intracellular signaling pathways. Research on this target encompasses X-linked intellectual disability, where loss-of-function mutations are implicated, along with glioblastoma invasion, melanoma progression, and T-cell activation biology. The antibody detects endogenous TSPAN7 in cell lysates by WB and visualizes subcellular localization by IF on fixed cells or tissue cryosections.

For Western blot, protein samples are commonly resolved under reducing conditions and probed at working dilutions calibrated for chemiluminescent or fluorescent readout. Immunofluorescence workflows benefit from the unconjugated format, allowing laboratories to pair the reagent with a preferred secondary antibody for multiplex imaging panels. Lot-specific validation data and recommended starting dilutions are available on the Antibodies.com product page.