Anti-TSPAN13 Antibody

TSPAN13 (Tetraspanin 13) is a transmembrane scaffolding protein of the tetraspanin superfamily that organizes specialized plasma membrane microdomains. This unconjugated rabbit polyclonal antibody from Antibodies.com, supplied as a 100 µl vial, was generated for Western blot (WB) and immunohistochemistry (IHC) detection of TSPAN13 in human, mouse, and rat samples.

Within tetraspanin-enriched microdomains (TEMs), TSPAN13 laterally associates with integrins, immunoglobulin superfamily receptors, and signaling molecules, influencing cell adhesion, motility, and intracellular communication. Investigators in membrane biology, neuronal development, and tumor biology contexts employ anti-TSPAN13 antibodies to map tissue distribution, examine co-fractionating partners via co-immunoprecipitation, and explore how altered TSPAN13 levels correlate with disease phenotypes.

Because the reagent is polyclonal, the rabbit host produces a heterogeneous population recognizing several regions of TSPAN13, supporting detection of distinct isoforms and post-translational variants. For stability, store refrigerated and protect from light; aliquot upon first use and limit freeze-thaw cycles. This product is intended for research use only.