Anti-TSC22D3 Antibody

Antibodies.com offers this affinity-purified rabbit polyclonal reagent raised against TSC22 domain family member 3, also known as GILZ (glucocorticoid-induced leucine zipper), a transcriptional regulatory protein that mediates anti-inflammatory signaling downstream of glucocorticoid receptor activation. The unconjugated IgG preparation is supplied at 100 µL volume and is validated for Western blot (WB) and immunofluorescence (IF) workflows on human samples, where it detects endogenous TSC22D3 expression in cell lysates and fixed cell preparations. The polyclonal antibody recognizes the native TSC22D3 isoform and is commonly deployed by investigators to probe glucocorticoid-responsive pathways, immune cell differentiation, and stress-associated transcriptional regulation in basic and translational research. The polyclonal format provides epitope diversity that is useful when probing multiple isoforms or post-translationally modified variants of TSC22D3 across different experimental contexts. Handling guidance recommends brief centrifugation of the vial before first use, and storage protected from light preserves reagent integrity across multiple freeze-thaw cycles of working aliquots.