Anti-Trx2 Antibody

Thioredoxin 2 (Trx2) is a mitochondria-resident redox regulator that defends cells against oxidative damage and supports mitochondrial homeostasis. This polyclonal reagent from Antibodies.com is raised in rabbit hosts and supplied as an unconjugated, liquid preparation at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, packaged as a 100 µl vial.

Immunoreactivity has been confirmed in human, mouse, and rat samples, so the antibody can be used across standard mammalian model systems as well as human tissue studies. Validated workflows include western blot, immunohistochemistry, and immunofluorescence, giving laboratories flexibility to localize Trx2 protein by microscopy, resolve it by gel electrophoresis, or detect it in fixed tissue sections.

Researchers commonly deploy this antibody to probe mitochondrial redox biology, to investigate apoptosis pathways linked to oxidative stress, and to examine Trx2 expression in disease models involving neurodegeneration, cardiovascular injury, and metabolic dysfunction. The polyclonal format broadens epitope coverage and improves the likelihood of a robust signal when target abundance is low, while the unconjugated format lets users pair the reagent with their preferred reporter-labeled secondary antibody for any of the supported detection chemistries.