Anti-Trx Antibody

The Anti-Trx polyclonal reagent from Antibodies.com is a rabbit host primary antibody raised against Thioredoxin (Trx), a small redox-active enzyme implicated in cellular oxidative stress response, DNA synthesis, and inflammatory signaling. Supplied as an unconjugated preparation at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2, this reagent is validated for Western blot applications in lysate and tissue homogenate samples. Cross-reactivity is confirmed against human, mouse, and rat Trx, supporting translational studies that span cell culture models and rodent disease research. The 50 µl pack volume provides ample reagent for multiple immunoblotting experiments when diluted per standard protocols. For handling, keep the vial refrigerated and protect from light; avoid repeated freeze-thaw cycles to maintain antibody binding activity. Trx expression is commonly interrogated in studies of antioxidant defense, apoptosis regulation, and cancer biology, where altered thioredoxin levels often correlate with disease severity and therapeutic response.