Anti-TRUB2 Antibody

This polyclonal primary antibody from Antibodies.com targets TRUB2 (TruB pseudouridine synthase family member 2), a mitochondrial pseudouridine synthase responsible for post-transcriptional pseudouridylation of mitochondrial mRNAs. Produced in rabbit and supplied as an IgG polyclonal reagent, the unconjugated antibody is validated for Western blot detection of the human TRUB2 protein. Each vial contains 100 µl of ready-to-use antiserum, supplied in a single-use format suitable for immunoblotting of human cell and tissue lysates.

TRUB2 has been linked to mitochondrial RNA metabolism and has emerged as a research target in studies of mitochondrial gene expression, oxidative phosphorylation, and certain cancer cell contexts where pseudouridine modification patterns are altered. Researchers investigating mitochondrial translation, RNA modification biology, or the broader family of pseudouridine synthases (PUS enzymes) use this reagent to probe TRUB2 expression across human samples. The unconjugated format allows flexibility with custom secondary antibody labeling and detection chemistries, including HRP, fluorescent, or biotin-based systems commonly used in standard Western blot workflows.

Storage recommendations typically include aliquoting upon arrival and freezing at -20 °C to preserve antibody activity across multiple experiments. As an IgG isotype produced in rabbit, the antibody is intended for research use only and is reactive with human TRUB2, in line with the species reactivity information supplied on the product datasheet.