Anti-TRPV6 Antibody

TRPV6 is a highly calcium-selective member of the vanilloid subfamily of transient receptor potential (TRP) channels, primarily expressed in epithelia of the small intestine, kidney, and placenta, where it mediates transcellular calcium uptake from the lumen. This rabbit polyclonal primary antibody from Antibodies.com recognizes the human TRPV6 protein and is supplied as an unconjugated IgG preparation in a 200 µl volume, intended for Western blot detection of the channel in cell and tissue lysates. The reagent is widely used by researchers investigating intestinal calcium absorption, mineral homeostasis, and the well-documented upregulation of TRPV6 in prostate adenocarcinoma and other epithelial cancers, where the channel has been proposed as both a marker of disease progression and a candidate therapeutic target.