Anti-TRPM2 Antibody

Raised in rabbit against the TRPM2 ion channel, this unconjugated polyclonal antibody from Antibodies.com is formatted for western blot and immunofluorescence workflows on human samples. TRPM2 (transient receptor potential melastatin 2) is a calcium-permeable, ADP-ribose-activated non-selective cation channel implicated in oxidative-stress signaling, ischemic injury, and neuroinflammatory pathways, making it a frequent target in studies of stroke, neurodegeneration, and metabolic disease. The reagent is supplied as 100 µl of affinity-purified serum suitable for standard blotting and imaging protocols, and it pairs cleanly with HRP- or fluorophore-conjugated secondary antibodies. Researchers commonly apply it to investigate channel expression in neurons, immune cells, and pancreatic tissue, where TRPM2 modulates calcium influx, cytokine release, and parthanatos cell death. Storage at -20 °C in working aliquots helps preserve activity across repeated freeze-thaw cycles, and the unconjugated format gives full flexibility for downstream labeling.