Anti-TRPC1 Antibody

A primary antibody from Antibodies.com, this affinity-purified rabbit polyclonal IgG reagent recognizes the TRPC1 calcium-permeable cation channel that contributes to store-operated calcium entry in excitable and non-excitable cells. Validated for western blot and immunohistochemistry workflows, the unconjugated antibody supports mapping of TRPC1 distribution in brain, heart, vascular smooth muscle, and epithelial tissues.

Supplied as a 200 µl liquid vial in PBS buffer with glycerol and sodium azide, the IgG fraction pairs flexibly with user-selected secondary labels such as HRP, Alexa Fluor, or biotin conjugates. Cross-reactivity spans human, mouse, and rat samples, enabling translational studies that bridge rodent disease models with human specimens. Researchers commonly deploy this reagent to investigate mechanotransduction, receptor-operated calcium signaling, and STIM1-coupled store-operated channel gating in vascular smooth muscle cells and cardiomyocytes.

For optimal stability, aliquot upon receipt and store at -20 °C, minimizing freeze-thaw cycles to preserve epitope recognition throughout the reagent's shelf life. This product is intended for research use only.