Anti-TRPA1 Antibody

A rabbit polyclonal antibody to TRPA1 from Antibodies.com, raised against a synthetic peptide corresponding to a sequence within amino acids 850-950 of human TRPA1 (NP_015628.2). The reagent is of the IgG isotype, unconjugated, and is produced in a rabbit host. It is reactive with human, mouse and rat samples, and is validated by the manufacturer for Western blot (WB) and immunohistochemistry (IHC), with IF additionally listed under applications. Recommended working dilutions are 1:500-1:1,000 for WB and 1:50-1:200 for IHC.

Supplied as a liquid in phosphate buffered saline (pH 7.3) containing 50% glycerol and 0.02% sodium azide, the antibody is purified by affinity chromatography. It is provided at a lot-specific concentration and has a reported molecular weight of 128 kDa. The product ships at 4°C; on arrival it should be aliquoted and stored at -20°C, with freeze/thaw cycles avoided. Cited in 1 publication, the reagent is associated with published work describing TRPA1 expression in dental pulp tissue correlating with inflammation severity, and a proposed link between TRPA1 activation, calcium influx, mitochondrial dysfunction and pyroptosis in the context of pulpitis.