Anti-Trk B Antibody

Trk B (tropomyosin receptor kinase B) is a high-affinity neurotrophin receptor that transduces BDNF and NT-4/5 signaling through the nervous system. Antibodies.com provides this unconjugated rabbit polyclonal reagent to support neuroscience, neurodevelopment, and signal transduction research where phospho-Trk pathway activity is being interrogated.

The polyclonal antibody is raised in rabbit and supplied at 100 µl per vial as a research-use-only liquid format. Unconjugated presentation allows users to pair it with their preferred HRP, biotin, or fluorophore-labeled secondary reagent. Reactivity has been confirmed against human, mouse, and rat Trk B targets, making it broadly usable across common model organisms used in neuroscience laboratories.

Documented application areas span Western blot for protein-level analysis in lysates, immunohistochemistry on fixed tissue sections, immunofluorescence imaging of cultured neurons, and ELISA-based quantification. The reagent should be aliquoted and stored refrigerated; repeated freeze-thaw cycles should be avoided to preserve binding activity across multiple experiments.