Anti-TRIM69 Antibody

This rabbit polyclonal reagent from Antibodies.com targets TRIM69 (Tripartite Motif Containing 69), a RING-type E3 ubiquitin ligase built around the canonical RBCC domain architecture. TRIM69 has attracted research attention for its role in innate antiviral defense, where published work has described its capacity to restrict replication of specific retroviruses, and for emerging links to ubiquitin-dependent regulation of cell proliferation and tumor biology.

The antibody is supplied as a 100 µl volume at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, ready for direct use in western blot, immunohistochemistry on fixed tissue sections, and immunofluorescence staining. It has been validated to detect the human protein and shows reactivity with mouse and rat orthologs, supporting cross-species experimental work in standard laboratory models. The unconjugated format lets researchers select the secondary detection reagents and label chemistries best matched to their individual experimental setup.

Short-term storage at 4 °C is appropriate for routine use; for longer intervals, the glycerol-containing buffer supports frozen storage at -20 °C, with protection from light to preserve reagent integrity. Aliquoting is recommended to limit freeze-thaw cycles of the antibody vial.