Anti-TRIM63 Antibody

Manufactured by Antibodies.com, this rabbit polyclonal reagent is raised against the E3 ubiquitin-protein ligase TRIM63 (also known as MuRF-1, Muscle-specific RING finger protein 1), a key regulator of muscle protein turnover. The immunogen is a synthetic peptide derived from human TRIM63, and the antibody specifically detects the endogenous total TRIM63 protein in samples of human, mouse, and rat origin. Validated applications include Western blot (WB), immunocytochemistry/immunofluorescence (ICC/IF), and immunohistochemistry (IHC), making it a versatile tool for studying striated muscle biology, atrophy pathways, and ubiquitin ligase signaling. The antibody is supplied as an unconjugated IgG preparation at 1.0 mg/mL in phosphate-buffered saline (pH 7.4, without Mg²⁺ and Ca²⁺) containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol, and it has been purified by affinity chromatography against the immunogen. The catalog size offered is 50 µl, and the product is shipped on cold packs at 4°C; upon receipt it should be aliquoted and stored at -20°C, with repeated freeze/thaw cycles avoided to preserve activity. Intended for research use only, this polyclonal TRIM63 antibody from Antibodies.com is well suited for laboratories investigating cardiac and skeletal muscle homeostasis, MuRF-1-mediated ubiquitination, and related disease models.