Anti-TRIM47 Antibody

Raised in rabbit and supplied as an unconjugated polyclonal reagent, this Antibodies.com antibody recognizes the tripartite motif-containing 47 (TRIM47) protein, an E3 ubiquitin ligase that participates in innate immunity, inflammatory signaling, and tumor-promoting pathways including colorectal and non-small-cell lung cancer.

Validated for Western blot and immunohistochemistry, the antibody reacts with human and mouse TRIM47 and is widely used to probe expression changes in cell lysates and formalin-fixed tissue sections. Each vial contains 100 µL of antiserum sufficient for multiple experiments when aliquoted; storage at -20 °C in working aliquots with limited freeze-thaw cycles preserves binding activity.

Researchers commonly apply this reagent to study TRIM47 induction following cytokine stimulation or viral infection, to confirm knockdown and overexpression efficiency in transfected cell lines, and to investigate downstream NF-κB and STAT signaling. Pair with a species-matched HRP- or fluorophore-labeled secondary antibody for chemiluminescent or fluorescent detection. For research use only; intended for laboratory research applications.