Anti-TRIM37 Antibody

TRIM37 is a member of the tripartite motif (TRIM) family of E3 ubiquitin ligases. Loss-of-function mutations in the TRIM37 gene on chromosome 17q22 cause Mulibrey nanism, a rare autosomal recessive growth disorder, while gene amplification and overexpression have been observed in several cancers. This rabbit polyclonal antibody from Antibodies.com is supplied as an unconjugated 100 µl preparation raised against human TRIM37 and validated for western blot, immunohistochemistry, and immunofluorescence applications.

The antibody recognizes endogenous human TRIM37 in cultured cells and fixed tissue sections, supporting studies of ubiquitin-dependent signaling, peroxisomal biology, and tumor cell proliferation. Researchers investigating RING-B-box-coiled-coil domain architecture or TRIM37-driven oncogenic pathways can apply the reagent across multiple detection formats, and the unconjugated format allows direct conjugation to fluorophores or enzymes in user-defined assays.

For storage, keep the vial refrigerated at 4°C and aliquot on first use to limit freeze-thaw cycles, preserving antibody activity over the working shelf life.