Anti-TRIM33 (C-terminus) Antibody

This monoclonal antibody from Antibodies.com targets the C-terminal region of TRIM33, also known as TIF1γ or ectodermin, a RING-type E3 ubiquitin ligase implicated in TGF-β signal modulation, transcriptional intermediary factor activity, and the cellular DNA damage response. Produced in mouse hosts, the unconjugated reagent is supplied as 100 µl of purified immunoglobulin formulated in 0.1 M Tris-Glycine buffer (pH 7.4) with 150 mM NaCl, 0.2% sodium azide as preservative, and 50% glycerol for freeze-thaw stability. Validation data confirm Western blot performance on human samples, making the reagent suitable for detecting endogenous TRIM33 expression in whole-cell or nuclear lysates prepared from cultured lines. Researchers studying chromatin remodeling, hematopoietic differentiation, or TRIM family-mediated tumor suppression pathways frequently deploy this clone to assess full-length protein levels and to probe C-terminal processing events that distinguish TRIM33 from its paralogues such as TIF1α and TIF1β.