Anti-TRIB3 Antibody

This rabbit polyclonal antibody from Antibodies.com targets TRIB3 (Tribbles pseudokinase 3), an inactive pseudokinase that functions as a scaffolding adaptor in stress-sensing pathways. Validated for western blot, the reagent detects endogenous TRIB3 in human, mouse, and rat samples, making it useful for comparative studies of ER stress, insulin signaling, and NF-κB regulation across model systems.

Supplied as a 100 µl vial at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the unconjugated preparation is ready to dilute into standard immunoblotting workflows. Researchers investigating PERK–CHOP signaling, hepatic gluconeogenesis, or tumor cell survival often use this reagent to probe TRIB3 induction by nutrient deprivation, thapsigargin, tunicamycin, or palmitate challenge. The polyclonal format increases the likelihood of recognizing multiple epitopes, which is helpful when probing cleaved or post-translationally modified forms of the protein in cellular stress models.

Store refrigerated between uses; the glycerol cryoprotectant guards against freeze-thaw damage if longer-term storage at -20°C is preferred. Protect from light. A single-use aliquot strategy is recommended to preserve activity across multiple experiments.