Anti-TRDMT1 Antibody

This rabbit polyclonal antibody from Antibodies.com targets TRDMT1, the tRNA aspartic acid methyltransferase 1 protein also known as DNMT2. TRDMT1 catalyzes the methyltransferase modification of cytosine-38 on tRNA-Asp and has been characterized for additional roles in cellular stress responses, RNA processing, and translational regulation under oxidative and DNA-damaging conditions. Documented reactivity covers both human and mouse samples, supporting comparative studies between the two species.

Provided as 100 µl of unconjugated polyclonal IgG in a single vial, the reagent is intended for Western blot workflows. For optimal preservation, store the vial at -20 °C and keep it protected from light; aliquoting upon first thaw is advised to minimize freeze-thaw cycles that can degrade antibody activity. Before blotting, dilute into standard buffer formulations and apply to membrane-bound lysates following SDS-PAGE separation.

This primary antibody is suited to research programs in RNA modification biology, tRNA methylome studies, and the investigation of TRDMT1-linked mechanisms in oncogenesis and stress granule dynamics. It is recommended for laboratory research use only and is not intended for diagnostic or therapeutic applications.