Anti-Transmembrane protein 147 Antibody

The antibody targets transmembrane protein 147 (TMEM147), a conserved endoplasmic reticulum-resident membrane protein that functions as a component of the oligosaccharyltransferase complex, supporting N-linked glycosylation of nascent polypeptides. Raised in rabbit and supplied as an unconjugated polyclonal reagent, this Antibodies.com reagent recognizes both human and mouse TMEM147 and has been validated for western blot, immunohistochemistry, and immunofluorescence workflows. Each vial contains 100 µl of the antibody preparation, allowing flexible dilution across immunoblotting, tissue-section staining, and subcellular localization studies. Researchers investigating ER-associated processes, secretory pathway function, and glycosylation-dependent signaling use this reagent to probe TMEM147 expression in cultured mammalian cells and tissue samples, where it helps map steady-state protein levels, monitor responses to ER stress, and characterize OST complex assembly under experimental perturbations.