Anti-TRAF7 Antibody

Raised in rabbit, this unconjugated polyclonal reagent targets the TRAF7 protein, an E3 ubiquitin ligase linked to NF-κB signaling and recurrently mutated in meningiomas. Validated for Western blot and immunohistochemistry on human samples, the antibody is supplied by Antibodies.com as a 100 µl aliquot. TRAF7 functions as a modulator of multiple receptor signaling pathways, supporting investigations into innate immunity, tumor biology, and ubiquitin-mediated regulation downstream of TNF receptor family activation. The polyclonal format provides epitope diversity, which is advantageous when probing for splice variants or post-translationally modified forms of the target. Researchers commonly employ such antibodies to assess expression in patient-derived meningioma tissue, characterize TLR-linked responses, or map ubiquitination events in cell-based assays.