Anti-TRAF4 Antibody

TRAF4 is a cytoplasmic adaptor protein in the TNF receptor-associated factor family that links cell-surface receptors to downstream signaling cascades, including NF-kB and JNK pathways, and is essential during neural crest cell migration and neural tube closure. This unconjugated rabbit polyclonal reagent from Antibodies.com recognizes endogenous TRAF4 in human, mouse, and rat samples and is validated for western blot, immunohistochemistry, and immunofluorescence workflows, supporting studies of developmental biology, innate immunity, and tumor signaling research.

The antibody is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, a formulation that stabilizes the protein during storage at -20 degrees C and tolerates repeated freeze-thaw cycles. Each vial contains 100 ul of stock, sufficient for dozens of immunoblots on whole-cell lysates or for parallel staining of formalin-fixed tissue sections. Researchers investigating receptor-mediated signaling, embryonic morphogenesis, and altered TRAF4 expression in cancer cell lines use this reagent to map subcellular localization and to probe pathway activation in primary tissues.