Anti-TRAF3IP3 Antibody

TRAF3-interacting protein 3 (TRAF3IP3) is an adaptor molecule implicated in NF-κB and JNK signaling cascades downstream of TNF receptor activation, with published roles in lymphocyte activation, thymic selection, and innate antiviral responses. This unconjugated rabbit polyclonal reagent from Antibodies.com enables detection of the endogenous human protein in both denaturing western blot workflows and fixed-section immunohistochemistry applications.

Validated for human reactivity, the polyclonal antiserum recognizes multiple epitopes across TRAF3IP3, increasing tolerance for minor protein variants and partial degradation. The unconjugated format lets researchers pair the antibody with HRP, biotin, or fluorophore-conjugated secondary reagents suited to their detection platform. Each vial contains 100 µl of working reagent, sufficient for routine blotting and staining panels.

Suggested uses include characterizing TRAF3IP3 expression in immune cell lysates, profiling its distribution across lymphoid tissue sections, and probing downstream signaling outcomes in transfected cell models. Store refrigerated in working aliquots to limit freeze-thaw cycles and preserve antibody titer over multi-week experiments. For research use only.