Anti-TRAF3 Antibody

This polyclonal reagent from Antibodies.com is raised in rabbit against TNF receptor-associated factor 3 (TRAF3), an intracellular adaptor that couples Toll-like receptors, TNF receptors, and other TRAF family members to NF-κB activation and interferon regulatory factor signaling. Researchers studying innate immunity, B-cell maturation, antiviral responses, and lymphoma biology rely on this primary antibody to detect endogenous TRAF3 protein in human and mouse specimens. The unconjugated preparation is supplied at 100 µl per vial and is validated for western blot, immunohistochemistry, and immunofluorescence workflows.

Because the antibody is rabbit polyclonal, it recognizes multiple epitopes across TRAF3, which is useful when probing low-abundance targets or partially degraded lysates. The unconjugated format leaves the choice of secondary open, so the same vial can be paired with HRP-, biotin-, or fluorophore-conjugated secondaries depending on whether the application is WB, IHC, or IF.

Reactivity is confirmed against human and mouse, covering the principal in vitro and in vivo models used in TRAF3 research, including studies of viral sensing pathways, autoimmunity, and B-cell lymphoma. Detailed handling notes and lot-specific quality data are documented on the product datasheet from Antibodies.com.