Anti-TRAF1 Antibody

TRAF1 (TNF Receptor-Associated Factor 1) is an intracellular adaptor protein that bridges members of the TNF receptor superfamily to downstream signaling pathways, most notably the NF-κB and JNK cascades. This unconjugated rabbit polyclonal reagent from Antibodies.com was raised against TRAF1 and is validated for Western blot and immunohistochemistry on human samples. The antibody is supplied at 100 µl per vial and is intended for research use only, supporting studies of immune receptor signaling, lymphocyte activation, apoptosis regulation, and inflammatory responses. TRAF1 expression is frequently examined in lymphoid malignancies, autoimmune disorders, and viral infection models, where its contribution to NF-κB activation and survival signaling can shape downstream cellular outcomes. Researchers probing TRAF1-dependent signaling in immune cells can use this reagent to detect endogenous levels of the protein in human-derived tissue sections and cell line lysates, making it a practical tool for immunohistochemistry and Western blot workflows in immunology and oncology laboratories.