Anti-TRADD Antibody

This polyclonal antibody from Antibodies.com targets TRADD (TNFRSF1A-Associated Death Domain), a 34 kDa cytoplasmic adapter that links TNF receptor 1 to downstream effectors. Raised in rabbit against the human protein, the unconjugated reagent is supplied as 100 µl of ready-to-use reagent validated in western blot, immunohistochemistry, and immunofluorescence workflows on human samples. TRADD recruits TRAF2 and RIPK1 to drive NF-κB signaling and simultaneously engages FADD to initiate caspase-8-mediated apoptosis, making this reagent useful for mapping death receptor signaling networks, screening TNF-driven inflammatory responses, and characterizing necroptosis pathway components in fixed or lysed cell preparations.