Anti-TPSAB1 Antibody

The TPSAB1 target encodes both alpha and beta tryptase isoforms, serine proteases that are the most abundant proteins stored within mast cell secretory granules. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against TPSAB1 and is validated for western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) workflows in human samples, supporting studies of mast cell activation, allergic inflammation, systemic mastocytosis, and hereditary alpha-tryptasemia. Supplied at 100 µl, the polyclonal format provides broader epitope coverage for detecting endogenous tryptase in tissue sections and cell preparations, with reactivity limited to human antigen. Researchers investigating mast cell density in skin biopsies, tryptase release kinetics in anaphylaxis models, or tryptase expression in tumor microenvironment studies can apply this antibody to both fixed-tissue and lysate-based detection. The unconjugated format allows flexibility in choosing secondary detection systems and fluorophore or enzyme conjugates appropriate to the chosen assay platform.