Anti-TPSAB1 Antibody

Mast cell research depends on faithful detection of the protease-rich secretory granules that define these innate immune cells. Tryptase alpha/beta 1, encoded by TPSAB1, is the dominant protein component of human mast cell granules and serves as a long-standing histological marker for mast cell burden in tissue sections. This rabbit polyclonal antibody from Antibodies.com is raised against TPSAB1 and is validated for western blot, immunohistochemistry, and immunofluorescence workflows across human, mouse, and rat samples. Each vial contains 100 µl of unconjugated antibody at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as stabiliser, ready to dilute into standard lysis, blocking, or antibody diluent formulations. Polyclonal reactivity against multiple TPSAB1 epitopes supports consistent labelling of mast cells in protein lysates and fixed tissue, supporting studies of allergic inflammation, asthma, anaphylaxis, mastocytosis, and related inflammatory or fibrotic conditions where tryptase levels are tracked quantitatively.