Anti-TPP2 Antibody

Raised in rabbit and supplied as an unconjugated liquid preparation, this primary antibody from Antibodies.com targets tripeptidyl peptidase 2 (TPP2), a large cytoplasmic serine peptidase involved in cytosolic protein turnover, MHC class I antigen processing, and cell-cycle regulation. The reagent is provided at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, packaged in a 100 µl vial suitable for use across multiple Western blot and immunohistochemistry experiments.

TPP2 removes N-terminal tripeptides from polypeptides and has attracted research attention because altered expression is associated with several malignancies and specific neurodegenerative settings, making reliable detection reagents valuable for oncology and immunology laboratories. This polyclonal reagent has been validated against endogenous TPP2 in human, mouse, and rat samples, supporting cross-species comparative work and consistent staining or blotting across common model systems.

Because the antibody is unconjugated, researchers can couple it to their preferred reporter, including HRP, biotin, or fluorescent tags, to match existing detection workflows. Aliquoting upon receipt is recommended to limit freeze-thaw cycles of the glycerol-stabilized stock, helping preserve activity for long-term WB and IHC campaigns.