Anti-TPM4 Antibody

This rabbit polyclonal antibody targets TPM4 (tropomyosin 4), a cytoskeletal actin-binding protein that stabilizes actin filaments and modulates their interactions with other binding partners in non-muscle cells. TPM4 is implicated in cytoskeletal organization, cell motility, vesicle trafficking, and several cancer-related pathways where isoform switching alters actin dynamics. The unconjugated IgG reagent is part of the Antibodies.com catalogue of primary antibodies.

Supplied as a 50 µL aliquot, the antibody is validated for western blot detection of endogenous TPM4 in mouse and rat samples. The polyclonal format provides recognition of multiple epitopes on the tropomyosin 4 protein, which can be advantageous when probing denatured lysates by immunoblotting.

Reactivity has been confirmed against mouse and rat TPM4. Typical workflows involve lysing cells or tissues in standard RIPA buffer, separating proteins by SDS-PAGE, transferring to a membrane, and probing at a working dilution optimized for chemiluminescent detection. Store the vial refrigerated and avoid repeated freeze-thaw cycles to preserve antibody activity.