Anti-TPM3 Antibody

This rabbit polyclonal antibody from Antibodies.com targets TPM3 (tropomyosin 3), an actin-binding protein expressed across human, mouse, and rat tissues. Supplied as 100 µL at 1 mg/mL in PBS with 0.1% sodium azide and 50% glycerol, the unconjugated reagent is validated for Western blot, immunohistochemistry, and immunofluorescence workflows in research settings.

TPM3 is a key component of the actin cytoskeleton, contributing to the regulation of microfilament function in both muscle and non-muscle cells. Aberrant TPM3 expression and fusion events have been linked to nemaline myopathy, certain sarcomas, and tumor cell migration studies, making it a relevant target for investigations into skeletal muscle development, cancer biology, and cytoskeletal organization.

As a polyclonal reagent, the antibody recognizes multiple epitopes on the TPM3 protein, supporting robust signal detection across diverse sample types. Storage at -20 °C is recommended for long-term stability, with freeze-thaw cycles minimized to preserve activity. Researchers commonly apply dilutions in the range appropriate for the chosen assay format, using standard chromogenic or fluorescent detection systems.