Anti-TPH1 Antibody

Manufactured by Antibodies.com, this affinity-purified polyclonal reagent is raised in rabbit against a synthetic peptide derived from human tryptophan5-hydroxylase 1 (TPH1) surrounding the non-phosphorylation site at serine 260, enabling sensitive detection of endogenous TPH1 protein. The unconjugated IgG antibody is supplied as a 50 µl liquid at 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA, and 0.02% sodium azide, and is shipped at 4 °C for immediate aliquoting and storage at –20 °C with avoidance of freeze/thaw cycles. Verified applications include Western blot, immunohistochemistry (IHC), immunocytochemistry/immunofluorescence (ICC/IF), and ELISA, and the antibody has been validated for reactivity across human, mouse, and rat samples. The reagent recognizes full-length TPH1 (also known as TPH, TPRH, TRPH, or tryptophan 5-monooxygenase 1), the rate-limiting enzyme in peripheral serotonin biosynthesis, making it a useful tool for research into serotonin signalling, enteric neurobiology, and related metabolic pathways. For research use only; not intended for diagnostic or therapeutic applications.