Anti-TPD52L1 Antibody

Members of the Tumor Protein D52-Like (TPD52) family, including the TPD52L1 isoform also known as D53, regulate vesicular transport and proliferative signaling in epithelial cells, making them frequent targets of immunofluorescence staining studies in oncology and cell biology laboratories. This polyclonal IgG reagent from Antibodies.com is raised in rabbit against human TPD52L1, is unconjugated for direct coupling to user-preferred fluorophores, and is supplied as a 50 µl liquid aliquot. For research use only.

The antibody is validated for IF applications on human samples, including formalin-fixed or methanol-fixed cell lines, and pairs cleanly with host-matched secondary antibodies in multi-color imaging panels. TPD52L1 has been most extensively studied in breast carcinoma, prostate cancer, and head-and-neck squamous cell carcinoma research, where it serves as a marker of altered endocytic flux and receptor recycling. Typical co-stains include compartment markers such as early endosome antigen 1 and LAMP1, or proliferation markers like Ki-67, allowing subcellular mapping and lineage comparisons within a single imaging session. The vial should be refrigerated upon arrival, protected from light, and divided into single-use aliquots to limit freeze-thaw cycles and preserve lot-to-lot consistency across extended studies.