Anti-TP63 Antibody

This rabbit polyclonal antibody targets TP63, a p53-family transcription factor with critical roles in epithelial development, stem cell maintenance, and tumor suppression. Produced by Antibodies.com as an unconjugated primary antibody, it is supplied as 100 µl and validated for western blot (WB) and immunohistochemistry (IHC) workflows. The reagent shows reactivity against human, mouse, and rat samples, supporting cross-species studies of squamous epithelia, basal cell layers, and TP63-associated cancers including squamous cell carcinoma, as well as select breast and bladder tumor types. Because the target is implicated in developmental syndromes and oncogenesis, researchers commonly apply this reagent to characterize tissue-specific expression, investigate TAp63 versus ΔNp63 isoform switching, and probe apoptosis-related signaling pathways in cell culture and tissue sections.