Anti-TP53I11 Antibody

This unconjugated rabbit polyclonal antibody targets TP53I11, a p53-responsive protein studied in tumor suppressor signaling and stress-induced apoptosis pathways. Supplied as a 100 µL liquid aliquot by Antibodies.com, the reagent is validated for Western blot and immunohistochemistry workflows, with reactivity confirmed against human, mouse, and rat samples.

The polyclonal format offers multi-epitope recognition, which can be advantageous when working with formalin-fixed paraffin-embedded tissue sections or low-abundance targets in immunoblotting. Researchers investigating p53 network activation, DNA damage response, or chemoresistance mechanisms use this reagent to compare expression patterns between tumor and matched normal tissue, or between treated and untreated cell populations.

Because the antibody is supplied unconjugated, individual laboratories can pair it with their preferred secondary detection chemistry, including HRP, alkaline phosphatase, biotin, or fluorophore conjugates. To preserve activity, the vial should be aliquoted upon arrival and stored refrigerated; repeated freeze-thaw cycles should be avoided. Each unit is intended for research use only, supporting in vitro studies of cancer biology, cell cycle regulation, and p53-dependent transcriptional programs.