Anti-TP53BP1 Antibody

Manufactured by Antibodies.com, this rabbit polyclonal antibody targets TP53BP1 (also known as TP53-binding protein 1) and is supplied at 1.0 mg/mL in a 50 µl volume. The reagent was raised against a recombinant human RAD51 immunogen and affinity-purified using the same immunogen, and it specifically detects endogenous levels of total TP53BP1 protein. It is unconjugated and of the IgG isotype, presented in a phosphate-buffered saline formulation at pH 7.4 containing 150 mM sodium chloride, 0.02% sodium azide, and 50% glycerol as a cryoprotectant. The antibody is validated for Western blot (WB) and immunohistochemistry (IHC) applications and shows reactivity with human, mouse, and rat samples, making it suitable for cross-species studies of DNA damage response and chromatin biology where 53BP1 plays a central role. For handling, the vial is shipped at 4°C and should be aliquoted and stored at –20°C upon arrival, with repeated freeze/thaw cycles avoided to preserve activity. Each lot is intended for research use only and is not approved for diagnostic or therapeutic applications. Orders are dispatched from St. Louis, Missouri, with a typical lead time of six to nine business days. Together, these specifications make this Antibodies.com polyclonal a reliable choice for laboratories investigating the TP53BP1-dependent pathways involved in double-strand break repair, checkpoint signaling, and V(D)J recombination.