Anti-TP53 Antibody [Assigned #A10610]

The Antibodies.com mouse monoclonal targets the TP53 tumor suppressor (p53), enabling detection of wild-type and mutant forms in human cells and tissue. Supplied as 50 µL of unconjugated IgG, it is validated for Western blot, immunohistochemistry, and immunofluorescence workflows used in cancer biology and DNA damage response studies.

Store the antibody at -20 °C in working aliquots to limit freeze-thaw cycles, and protect from light. The host species is mouse, allowing use with anti-mouse secondary reagents in standard indirect detection protocols across each supported application.

This reagent fits research into p53-mediated apoptosis, cell-cycle arrest, and tumorigenesis pathways, including studies of Li-Fraumeni-associated mutations and chemotherapeutic responses. Pair it with appropriate positive controls such as doxorubicin-treated or UV-irradiated cell lines to confirm induction of stabilized p53, and include a negative control line (such as Saos-2, which lacks endogenous p53) for specificity assessment.