Anti-TORC1 Antibody

This Mouse monoclonal antibody from Antibodies.com targets TORC1 (Transducer of Regulated CREB activity 1, also designated CRTC1 or MECT1), a CREB transcriptional coactivator that mediates cAMP-dependent gene regulation and has been investigated in neuronal plasticity, metabolic control, and the biology of oncogenic MAML2 fusion events.

Supplied as a 100 µL unconjugated IgM preparation raised in Mouse, the reagent is validated for Western blot (WB) and Immunocytochemistry (ICC). It recognizes TORC1 in Human, Mouse, Monkey, and Rat samples, supporting comparative work across rodent disease models and primate or human cell systems.

Typical uses include confirming endogenous TORC1 expression in cell lysates, monitoring nuclear translocation after forskolin or cAMP stimulation, and profiling lines that carry CRTC1-driven transcriptional programs. Aliquot upon arrival and store refrigerated; avoid repeated freeze-thaw cycles of the stock to preserve binding activity.