Anti-TOMM20 Antibody [Assigned #A11308]

Supplied by Antibodies.com as a 200 µL liquid aliquot of unconjugated rabbit monoclonal IgG, this primary antibody recognizes TOMM20 (Translocase of Outer Mitochondrial Membrane 20), a 16 kDa outer-mitochondrial-membrane receptor that funnels nucleus-encoded preproteins into the TOM40 import channel. Clone #A11308 cross-reacts with human, mouse, and rat samples, enabling side-by-side comparisons across rodent disease models and human tissues in the same blot or imaging run.

Validated for western blot, immunohistochemistry, and immunofluorescence workflows, the reagent performs reliably on paraffin-embedded sections and cultured cell monolayers, producing the characteristic punctate cytoplasmic pattern expected of an outer-membrane marker. Researchers pair it with cytosolic or nuclear loading controls to normalize mitochondrial readouts across treatment arms, and it is widely used to monitor mitochondrial network remodelling during PINK1/Parkin-dependent mitophagy, outer-membrane permeabilization in apoptosis assays, and shifts in cellular bioenergetics under oxidative or pharmacological stress. The antibody is shipped in PBS with 50% glycerol and 0.02% sodium azide; store at -20°C, aliquot upon first thaw, and avoid repeated freeze-thaw cycles to preserve titre. For research use only, not intended for diagnostic or therapeutic applications.