Anti-TNS3 Antibody

Tensin 3 (TNS3) is a focal-adhesion phosphoprotein of the tensin family, and the rabbit polyclonal antibody from Antibodies.com offers a specific reagent for its detection in human samples. Supplied as 50 µl of unconjugated IgG in a single-use vial, this primary antibody is validated for western blot and is intended for research use only.

TNS3 links integrin signaling to the actin cytoskeleton through a C-terminal actin-binding region and an N-terminal PTB domain, and it also carries an SH2 module that engages phosphotyrosine motifs. The protein participates in cell-matrix adhesion, cytoskeletal remodeling, and downstream signaling cascades influencing cell migration, proliferation, and insulin-stimulated GLUT4 translocation in adipocytes. Altered TNS3 expression has been reported in renal cell carcinoma and several other tumor types, giving this reagent utility across cancer biology, signal transduction, and metabolic research programs.

Specifications: Rabbit host, polyclonal clonality, IgG isotype, unconjugated format, human reactivity, WB application, 50 µl vial. The reagent should be stored refrigerated in working aliquots to limit freeze-thaw cycles; protect the stock from light during handling.