Anti-TNNI3 Antibody

Cardiac troponin I (TNNI3) is a 24 kDa subunit of the troponin complex expressed almost exclusively in cardiac muscle tissue, where it regulates calcium-dependent actomyosin ATPase activity during contraction and relaxation.

This rabbit polyclonal antibody from Antibodies.com recognizes the cardiac isoform of troponin I and is validated for Western blot and immunohistochemistry on human and mouse samples. Supplied as 100 µL of unconjugated antiserum in a vial, the reagent supports studies of myocardial injury, ischemic heart disease, and inherited cardiomyopathies such as familial hypertrophic and restrictive cardiomyopathy linked to TNNI3 mutations.

Researchers investigating acute myocardial infarction biomarkers, troponin release kinetics, or cardiac differentiation in pluripotent stem cell-derived cardiomyocytes can deploy this reagent for both protein-level detection in tissue sections and immunoblotting of cell lysates. For research use only.