Anti-TNNC1 Antibody

This rabbit polyclonal antibody from Antibodies.com targets TNNC1, the cardiac and slow-twitch troponin C isoform that binds calcium and regulates actin-myosin cross-bridge cycling in striated muscle. Researchers investigating sarcomeric calcium handling, cardiomyocyte differentiation, or contractile dysfunction use this reagent to detect the endogenous protein in human samples by Western blot, immunohistochemistry, and immunofluorescence. The unconjugated IgG is supplied as 100 µl of antiserum, aliquoted for single-use sessions to limit freeze-thaw cycles and preserve affinity during long-term storage at -20 °C with brief 4 °C handling.

Validated on human tissue and cell lysates, the polyclonal format recognizes multiple epitopes across the troponin C molecule, improving signal recovery even when a single epitope is masked by fixation or denaturation. Pair the primary with an HRP- or fluorophore-conjugated secondary appropriate to the application; for immunofluorescence, common co-stains include α-actinin or phalloidin to visualize sarcomere organization alongside the troponin signal. Each lot is affinity-purified and quality-controlled by the manufacturer to deliver consistent performance across blots and sections for research use only.