Anti-TNFSF15 Antibody

The Antibodies.com polyclonal reagent targets human TNFSF15, a TNF-superfamily cytokine also referenced as TL1A or VEGI that contributes to inflammatory signaling, mucosal immunity, and angiogenic regulation. Raised in rabbit, this unconjugated antibody is supplied as 100 µl of antiserum and is validated for western blot and immunofluorescence workflows against human samples.

TNFSF15 signals through the DR3 receptor (TNFRSF25) and has been investigated in inflammatory bowel disease, rheumatoid arthritis, psoriasis, and tumor microenvironment studies, making this reagent useful for researchers exploring cytokine-driven immune pathways. The polyclonal format offers broader epitope coverage for detecting endogenous TNFSF15 in cell lysates and fixed tissue sections.

For western blot, samples are typically prepared in standard lysis buffer, separated by SDS-PAGE, and transferred to nitrocellulose or PVDF membranes. For immunofluorescence, the unconjugated format enables flexible pairing with fluorophore-conjugated secondary antibodies matched to specific imaging platforms.