Anti-TNFSF12 Antibody

The Antibodies.com rabbit polyclonal antibody against TNFSF12, also known as TWEAK, is supplied as 100 µl of unconjugated polyclonal reagent raised in a rabbit host. The TNFSF12 ligand is a type II transmembrane cytokine of the TNF superfamily that signals through the Fn14 receptor, driving inflammatory cascades, angiogenic remodeling, and proliferation pathways in epithelial, endothelial, and immune cells.

Validated for western blot and immunohistochemistry on human, mouse, and rat specimens, this primary antibody detects the full-length ~27 kDa TNFSF12 protein and its cleaved soluble fragment, supporting studies in renal injury, cardiac remodeling, autoimmune inflammation, and tumor microenvironment models. For best retention of polyclonal reactivity, store refrigerated between experimental runs and minimize freeze-thaw cycles, as the reagent is intended for research use only and is not cleared for diagnostic procedures.